At least 10 people were shot Friday in front of the Empire State Building, according to the New York Office of Emergency Management.
A fire department spokesman says it received a call about the shooting just after at 9 a.m. Friday and that emergency units were on the scene within minutes and converged on the building.
Aliyah Imam tells Fox 5 News that she was standing at a red light when a woman standing next to her fell to the ground. She says the woman was hit in the hip. She says the gunman was "shooting indiscriminately at people."
New York resident Max Kaplan, 22, said he heard at least nine gunshots. He said several ambulances have arrived at the scene.
"We're all very shaken up at the office," he said.
The gunman was shot and killed by police, the New York Police Department reported.
It is not clear what the casualties' conditions were, or what led to the shooting at 34th Street and Fifth Avenue. The incident does not appear to be terror-related, police said.
There is currently a heavy police presence around the popular tourist attraction.
Fifth Avenue, a major traffic artery in the city, has been closed from 42nd street, local media said.
The Empire State Building is one of the most famous skyscrapers in the world, and one of New York City's best-known tourist attractions. Each year, about 4 million people visit the building's two observation decks. At more than 1,453 feet tall, the landmark building reaches more than a quarter-mile into the sky.