Durant scored 41 points and grabbed 13 rebounds, while Russell Westbrook's recorded 27 points and 11 assists to help the Thunder improve their league-best record to 21-4.
The league's second best winning streak kept rolling too as the Los Angeles Clippers made it 11 in a row with a 93-77 win over the New Orleans Hornets.
The Boston Celtics were 100-91 winners against the Cleveland Cavaliers, with Paul Pierce netting 40 points and Rajon Rondo adding 20.
Carmelo Anthony returned from an ankle injury to the New York Knicks in time to help them beat their city rivals, scoring 31 points in a 100-86 victory over the Brooklyn Nets.
DeMarcus Cousins scored 24 points to lead seven Sacramento Kings players in double figures in their 131-127 win over the Golden State Warriors. Stephen Curry had 32 points in a losing cause for the Warriors.
James Harden's rich vein of form continued as he scored 33 points in the Houston Rockets' 125-103 victory over the Philadelphia 76ers, who slipped to their fifth consecutive defeat.
The Charlotte Bobcats' miserable run continued as they suffered their 13th straight loss, this time going down 121-104 to the Phoenix Suns thanks to 26 points from Shannon Brown.
Elsewhere, the Toronto Raptors beat the Detroit Pistons 97-91, the Orlando Magic made it five wins in a row by beating the Washington Wizards 90-83, the Indiana Pacers beat the Utah Jazz 104-84 and the Memphis Grizzlies overcame the Milwaukee Bucks 90-80.