Orlando had been trailing at half-time at the Amway Center, but a 40-point haul in the third quarter turned the game in their favour.
JJ Redick scored 24 points for the victors, two more than team-mates Arron Afflalo and Glen Davis.
Kyle Lowry and DeMar DeRozan also scored 22 points as Toronto earned their first victory of the season, 105-86 against Minnesota.
The result means the Raptors have beaten the Timberwolves in 15 of their last 16 games, including nine in a row in Toronto.
Kevin Martin's 28 points were in vain for the Oklahoma City Thunder, beaten 104-95 by the Atlanta Hawks - for whom Al Horford led the way with 23.
Carmelo Anthony scored 27 points as the New York Knicks continued their promising start to the campaign with a 100-84 victory over the Philadelphia 76ers, for whom Jrue Holiday also netted 27.